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DriverRWH: Discovering Cancer Driver Genes By Random Walk On a Gene Mutation Hypergraph

2021-12-30

Abstract excerpt

<h4>Background: </h4> Recent advances in next-generation sequencing technologies have helped investigators generate massive amounts of cancer genomic data. A critical challenge in cancer genomics is identification of a few driver mutation genes from a much larger number of passenger mutation genes. However, majority of existing computational approaches underuse the co-occurrence information of the individuals, whi...

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Literature Corpus work
34e59e74-fa5a-5e09-a869-07acb8e10fbf
DOI
10.21203/rs.3.rs-1192205/v1
Open publication

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DriverRWH: Discovering Cancer Driver Genes By Random Walk On a Gene Mutation HypergraphDOI 10.21203/rs.3.rs-1192205/v1
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