ONCOPLEX: an oncology-inspired hypergraph model integrating diverse biological knowledge for cancer driver gene prediction.

Abstract excerpt

Cancer development is driven by a small subset of somatic mutations, known as driver mutations, that disrupt key regulatory processes in cells. These mutations occur in specific genes, called cancer driver genes, whose altered functions promote tumor initiation and progression. Accurately identifying driver genes remains a major challenge due to their rarity and the overwhelming presence of passenger mutations....

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