Article
Exploring gene-patient association to identify personalized cancer driver genes by linear neighborhood propagation.
BMC bioinformatics - 22 Jan 2024
Huang Yiran, Chen Fuhao, Sun Hongtao, Zhong Cheng
Abstract excerpt
BACKGROUND: Driver genes play a vital role in the development of cancer. Identifying driver genes is critical for diagnosing and understanding cancer. However, challenges remain in identifying personalized driver genes due to tumor heterogeneity of cancer. Although many computational methods have been developed to solve this problem, few efforts have been undertaken to explore gene-patient associations to...
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