Article
PersonaDrive: A Method for the Identification and Prioritization of Personalized Cancer Drivers
2021-10-12
Abstract excerpt
<h4>Motivation</h4> A major challenge in cancer genomics is to distinguish the driver mutations that are causally linked to cancer from passenger mutations that do not contribute to cancer development. The majority of existing methods provide a single driver gene list for the entire cohort of patients. However, since mutation profiles of patients from the same cancer type show a high degree of heterogeneity, a mo...
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Identifiers and source
- Literature Corpus work
- 10543c54-f966-5ea5-8bfe-0126dc97c044
- DOI
- 10.1101/2021.10.11.463919