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Article

Identifying cooperating cancer driver genes in individual patients through hypergraph random walk.

Journal of biomedical informatics - 1 Sept 2024

Zhang Tong, Zhang Shao-Wu, Xie Ming-Yu, Li Yan

Abstract excerpt

OBJECTIVE: Identifying cancer driver genes, especially rare or patient-specific cancer driver genes, is a primary goal in cancer therapy. Although researchers have proposed some methods to tackle this problem, these methods mostly identify cancer driver genes at single gene level, overlooking the cooperative relationship among cancer driver genes. Identifying cooperating cancer driver genes in individual patients...

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PMID: 39159864
DOI: 10.1016/j.jbi.2024.104710

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