Article
VarWalker: personalized mutation network analysis of putative cancer genes from next-generation sequencing data.
PLoS computational biology - 1 Feb 2014
Jia Peilin, Zhao Zhongming
Abstract excerpt
A major challenge in interpreting the large volume of mutation data identified by next-generation sequencing (NGS) is to distinguish driver mutations from neutral passenger mutations to facilitate the identification of targetable genes and new drugs. Current approaches are primarily based on muta...
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