Article

High-throughput Oligopaint screen identifies druggable regulators of genome folding

2022-04-10

Abstract excerpt

<h4>Summary</h4> Although the molecular rules governing genome organization are being quickly elucidated, relatively few proteins regulating this process have been identified. To address this gap, we developed a fully automated imaging pipeline, called HiDRO (high-throughput DNA or RNA labeling with optimized Oligopaints), that permits quantitative measurement of chromatin interactions across a large number of sa...

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Literature Corpus work: 33932943-08e0-5120-b1df-047442870e21
DOI: 10.1101/2022.04.08.487672

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