Article

Ultrastructural details of mammalian chromosome architecture

2019-05-17

Abstract excerpt

<h4>ABSTRACT</h4> Over the past decade, 3C-related methods, complemented by increasingly detailed microscopic views of the nucleus, have provided unprecedented insights into chromosome folding in vivo. Here, to overcome the resolution limits inherent to the majority of genome-wide chromosome architecture mapping studies, we extend a recently-developed Hi-C variant, Micro-C, to map chromosome architecture at nucle...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6b6149ef-ce1d-5fdf-b2f0-bbf8665f4c49
DOI: 10.1101/639922

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ultrastructural details of mammalian chromosome architectureDOI 10.1101/639922Read

Helical Coiled Nucleosome Chromosome Architectures during Cell Cycle ProgressionSemantic proximity Read

Molecular architecture of heterochromatin at the nuclear periphery of primary human cellsSemantic proximity Read

Walking along chromosomes with super-resolution imaging, contact maps, and integrative modelingSemantic proximity Read

Deciphering histone mark-specific fine-scale chromatin organization at high resolution with Micro-C-ChIPSemantic proximity Read

Sister-chromatid-sensitive Hi-C reveals the conformation of replicated human chromosomesSemantic proximity Read

Mitotic chromosomes harbor cell type and species-specific structural features within a universal looping architectureSemantic proximity Read

Nanoscale analysis of human G1 and metaphase chromatin <i>in situ</i>Semantic proximity Read

Comparison of the 3D organization of sperm and fibroblast genomes using the Hi-C approachSemantic proximity Read

An integrated view of the structure and function of the human 4D nucleomeSemantic proximity Read

Nanoscale 3D DNA tracing in single human cells visualizes loop extrusion directly in situSemantic proximity Read

Perturb-tracing enables high-content screening of multiscale 3D genome regulatorsSemantic proximity Read

HiCTMap: Detection and Analysis of Chromosome Territory Structure and Position by High-throughput ImagingSemantic proximity Read