Article

Nucleic acid sequence determinants of transcriptional pausing by human mitochondrial RNA polymerase (POLRMT)

2025-04-26

Abstract excerpt

<h4>ABSTRACT</h4> Transcription by RNA polymerase (RNAP) lies at the heart of gene expression in all organisms. The speed with which RNAPs produce the RNA is tuned in part by the signals in the transcribed nucleic-acid sequences, which temporarily arrange RNAPs into a paused conformation unable to extend the RNA. In turn, the altered transcription kinetics determines the three-dimensional shape into which RNA ult...

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Literature Corpus work: 31b66a2e-5b4d-5f74-bf4b-9128dfbb5770
DOI: 10.1101/2025.04.25.650729

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