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Article

A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae.

Genetics - 1 Jul 2008

Andersen Marguerite P, Nelson Zara W, Hetrick Elizabeth D, Gottschling Daniel E

Abstract excerpt

Loss of heterozygosity (LOH) can be a driving force in the evolution of mitotic/somatic diploid cells, and cellular changes that increase the rate of LOH have been proposed to facilitate this process. In the yeast Saccharomyces cerevisiae, spontaneous LOH occurs by a number of mechanisms including chromosome loss and reciprocal and nonreciprocal recombination. We performed a screen in diploid yeast to identify...

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Source

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Identifiers

PMID: 18562670
DOI: 10.1534/genetics.108.089250
PMCID: PMC2475725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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