Back to search

Article

Studies on the International Space Station to assess the effects of microgravity on iPSC-derived neural organoids

2023-08-14

Abstract excerpt

Exposure to microgravity in low-Earth orbit (LEO) has been shown to affect human cardiovascular, musculoskeletal, and immune systems. Post-flight brain imaging indicates that reports about astronauts and mouse models suggest that microgravity may cause intracranial fluid shifts and possibly alter white and gray matter of the brain [1]. To focus on the effects of microgravity on the brain, we used induced pluripote...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2e5764c0-9941-5d8b-b0c8-64438ca9632f
DOI
10.1101/2023.08.10.552814
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Studies on the International Space Station to assess the effects of microgravity on iPSC-derived neural organoidsDOI 10.1101/2023.08.10.552814
Effects of microgravity on human iPSC-derived neural organoids on the International Space StationSemantic proximity
Integration of iPSC-derived microglia into human midbrain organoids enhances microglial maturation and inflammatory signalingSemantic proximity
A glia-enriched stem cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosis.Semantic proximity
Glia-enriched stem-cell 3D model of the human brain mimics the glial-immune neurodegenerative phenotypes of multiple sclerosisSemantic proximity
Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionalitySemantic proximity
A reproducible human brain tissue model to study physiological and disease-associated microglia phenotypesSemantic proximity
An Integrated Neuroimmune Assembloid Model to Advance Neurodegenerative Disease StudiesSemantic proximity
Defined human tri-lineage brain microtissuesSemantic proximity
Human spinal cord organoids recapitulate developmental and disease-associated oligodendrocyte lineage signaturesSemantic proximity
Developing Human Pluripotent Stem Cell-Based Cerebral Organoids with a Controllable Microglia Ratio for Modeling Brain Development and PathologySemantic proximity
A Human iPSC-derived Organoid System to Model Myelin Destruction and RepairSemantic proximity
Midbrain microglia-integrated organoids as a next-generation tool for chronic morphine withdrawal research: A pilot studySemantic proximity
Select a neighboring publication to make it the new centre.