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Effects of microgravity on human iPSC-derived neural organoids on the International Space Station

23 Oct 2024

Abstract excerpt

Research conducted on the International Space Station (ISS) in low-Earth orbit (LEO) has shown the effects of microgravity on multiple organs. To investigate the effects of microgravity on the central nervous system, we developed a unique organoid strategy for modeling specific regions of the brain that are affected by neurodegenerative diseases. We generated 3-dimensional human neural organoids from induced...

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PMID: 39441987
DOI: 10.1093/stcltm/szae070

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