Article

Image-based screens identify regulators of endogenous Dvl2 biomolecular condensates

2025-01-12

Abstract excerpt

<h4>Summary</h4> Dishevelled (Dvl) proteins are essential transducers in Wnt signaling pathways, which have been implicated in development, stem cell maintenance, and human diseases such as cancer. Several studies have shown that Dvl proteins form dynamic biomolecular condensates. However, how cellular signals and cell states influence the formation of biomolecular condensates remains poorly understood. Here, we...

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Literature Corpus work: 2d764032-594a-51fd-a5df-bcc14acccfdf
DOI: 10.1101/2025.01.11.632522

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