Article
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling.
The Journal of biological chemistry - 29 Mar 2013
González-Sancho José M, Greer Yoshimi Endo, Abrahams Cristina L, Takigawa Yutaka, Baljinnyam Bolormaa, Lee Kyung Ho, Lee Kyung S, Rubin Jeffrey S, Brown Anthony M C
Abstract excerpt
Dishevelled (Dvl) proteins are intracellular effectors of Wnt signaling that have essential roles in both canonical and noncanonical Wnt pathways. It has long been known that Wnts stimulate Dvl phosphorylation, but relatively little is known about its functional significance. We have previously reported that both Wnt3a and Wnt5a induce Dvl2 phosphorylation that is associated with an electrophoretic mobility shift...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.