Article

Dynamic landscapes of gene regulatory networks in early mammalian neurogenesis: Insights into brain evolution and disorder risk

2025-10-08

Abstract excerpt

<h4>ABSTRACT</h4> Neurogenesis—the process of generating neurons—is governed by dynamic transcriptional programs that vary across time, brain regions, and cell types, forming regionally specialized neuronal circuits. To understand these dynamics, we constructed a comprehensive gene regulatory network (GRN) resource encompassing 22 neurogenic lineages from human, macaque, and mouse, enabling cross-species and cros...

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Literature Corpus work: d1585fd4-d0eb-5d08-a0a4-aba196bbfd34
DOI: 10.1101/2025.10.07.681016

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