Article

Inferring perturbation profiles of cancer samples

2020-12-10

Abstract excerpt

<h4>Motivation</h4> Cancer is one of the most prevalent diseases in the world. Tumors arise due to important genes changing their activity, e.g., when inhibited or over-expressed. But these gene perturbations are difficult to observe directly. Molecular profiles of tumors can provide indirect evidence of gene perturbations. However, inferring perturbation profiles from molecular alterations is challenging due to...

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Literature Corpus work: 2aa58d3a-2dfb-52b3-83e0-bdd44aed2571
DOI: 10.1101/2020.12.10.419077

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