Article

Identifying Network Perturbation in Cancer

2016-02-21

Abstract excerpt

We present a computational framework, called DISCERN ( DI fferential S pars E R egulatory N etwork), to identify informative topological changes in gene-regulator dependence networks inferred on the basis of mRNA expression datasets within distinct biological states. DISCERN takes two expression datasets as input: an expression dataset of diseased tissues from patients with a disease of interest and another ex...

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Literature Corpus work: 6c663e4c-553c-5853-9e9f-9b069f72ecec
DOI: 10.1101/040394

Open publication

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