Article

Autoimmunity associated allele of tyrosine phosphatase gene <i>PTPN22</i> enhances anti-viral immunity

2023-06-30

Abstract excerpt

<h4> Abstract </h4> The 1858C>T allele of the tyrosine phosphatase PTPN22 is present in 5-10% of the North American population and is strongly associated with numerous autoimmune diseases. Although research has been done to define how this allele potentiates autoimmunity, the influence PTPN22 and its pro-autoimmune allele has in anti-viral immunity remains poorly defined. Here, we use single cell RNA- sequenci...

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Literature Corpus work: 29f5cf09-4a7f-5ce9-9817-6a4014c4c501
DOI: 10.1101/2023.06.28.546768

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