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Article

Regulation of T Cell Signaling and Immune Responses by PTPN22.

Molecular and cellular biology - 1 Jan 2024

Brownlie Rebecca J, Salmond Robert J

Abstract excerpt

Protein tyrosine phosphatases (PTPs) play central roles in the regulation of cell signaling, organismal development, cellular differentiation and proliferation, and cancer. In the immune system, PTPs regulate the activation, differentiation and effector function of lymphocytes and myeloid cells whilst single-nucleotide polymorphisms (SNPs) in PTP-encoding genes have been identified as risk factors for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39039893
DOI: 10.1080/10985549.2024.2378810
PMCID: PMC11486154

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