Article

Single cell epigenomic atlas of the developing human brain and organoids

2019-12-31

Abstract excerpt

Dynamic changes in chromatin accessibility coincide with important aspects of neuronal differentiation, such as fate specification and arealization and confer cell type-specific associations to neurodevelopmental disorders. However, studies of the epigenomic landscape of the developing human brain have yet to be performed at single-cell resolution. Here, we profiled chromatin accessibility of >75,000 cells from ei...

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Literature Corpus work: c13c023b-7f01-5f5e-8b29-d41dd58557a2
DOI: 10.1101/2019.12.30.891549

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