Article

Extracellular matrix stiffness regulates fibroblast differentiation by influencing DNA methyltransferase 1 expression through microtubule polymerization

2022-10-20

Abstract excerpt

Cells sense physical cues, such as changes in extracellular matrix (ECM) stiffness, and translate these stimuli into biochemical signals that control various aspects of cellular behavior, thereby facilitating physiological and pathological processes in various organs. Evidence from multiple studies suggests that the anterior vaginal wall stiffness is higher in POP patients than in non-POP patients. Our experiments...

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Literature Corpus work: 29904c45-8d57-5e5e-b55c-1ce32dffabdb
DOI: 10.1101/2022.10.20.513009

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