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Molecular Cues Guiding Matrix Stiffness in Liver Fibrosis

1 Jan 2016

Abstract excerpt

Tissue and matrix stiffness affect cell properties during morphogenesis, cell growth, differentiation, and migration and are altered in the tissue remodeling following injury and the pathological progression. However, detailed molecular mechanisms underlying alterations of stiffness in vivo are still poorly understood. Recent engineering technologies have developed powerful techniques to characterize the...

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PMID: 27800489
DOI: 10.1155/2016/2646212

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