Article
CCSI: a database providing chromatin-chromatin spatial interaction information.
Database : the journal of biological databases and curation - 1 Jan 2016
Xie Xiaowei, Ma Wenbin, Songyang Zhou, Luo Zhenhua, Huang Junfeng, Dai Zhiming, Xiong Yuanyan
Abstract excerpt
Distal regulatory elements have been shown to regulate gene transcription through spatial interactions, and single nucleotide polymorphisms (SNPs) are linked with distal gene expression by spatial proximity, which helps to explain the causal role of disease-associated SNPs in non-coding region. Therefore, studies on spatial interactions between chromatin have created a new avenue for elucidating the mechanism of...
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