Article

Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice

2018-02-02

Abstract excerpt

<h4>Summary</h4> Xist is the master regulator of X chromosome inactivation (XCI). In order to further understand the Xist locus in reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) and in somatic cell nuclear transfer (SCNT), we tested transcription-factor-like effectors (TALE)-based designer transcriptional factors (dTFs), which were specific to numerous regions at the Xist locus. We rep...

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Literature Corpus work: 2781cfbc-6ce1-5e24-b761-64de6c35e92e
DOI: 10.1101/259234

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