Article

Construction of thousands of single cell genome sequencing libraries using combinatorial indexing

2016-07-23

Abstract excerpt

Single cell genome sequencing has proven to be a valuable tool for the detection of somatic variation, particularly in the context of tumor evolution and neuronal heterogeneity. Current technologies suffer from high per-cell library construction costs which restrict the number of cells that can be assessed, thus imposing limitations on the ability to quantitatively measure genomic heterogeneity within a tissue. He...

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Literature Corpus work: 2467f968-7457-5b9f-8192-9255b93401b2
DOI: 10.1101/065482

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