Article

Characterizing the allele- and haplotype-specific copy number landscape of cancer genomes at single-cell resolution with CHISEL

2019-11-10

Abstract excerpt

Single-cell barcoding technologies have recently been used to perform whole-genome sequencing of thousands of individual cells in parallel. These technologies provide the opportunity to characterize genomic heterogeneity at single-cell resolution, but their extremely low sequencing coverage (<0.05X per cell) has thus far restricted their use to identification of the total copy number of large multi-megabase segme...

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Literature Corpus work: 9f38cb93-99f8-558f-aafe-8ba736929d62
DOI: 10.1101/837195

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