Article

Parental allele-specific genome architecture and transcription during the cell cycle

2017-10-11

Abstract excerpt

A normal human somatic cell inherits two haploid genomes. Individual chromosomes of each pair have distinct parental origins and parental alleles are known to unequally contribute to cellular function. We integrated chromosome conformation (form) and gene transcription (function) analyses to dissect the dynamics of the maternal and paternal genomes in lymphoblastoid cells during the cell cycle. We found a distinct...

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Literature Corpus work: 2383e071-e4d0-508a-acdb-130533d4d5dd
DOI: 10.1101/201715

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