Article

Functional Organization of the Maternal and Paternal Human 4D Nucleome

2020-03-17

Abstract excerpt

Every human somatic cell inherits a maternal and a paternal genome, which work together to give rise to cellular phenotypes. However, the allele-specific relationship between gene expression and genome structure through the cell cycle is largely unknown. By integrating haplotype-resolved genome-wide chromosome conformation capture, mature and nascent mRNA, and protein binding data, we investigate this relationship...

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Literature Corpus work: 33e474e8-5779-55e2-a37e-2b9c4912f8fb
DOI: 10.1101/2020.03.15.992164

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