Article

Widespread allele-specific topological domains in the human genome are not confined to imprinted gene clusters

2022-04-27

Abstract excerpt

<h4>Background</h4> There is widespread interest in the three-dimensional chromatin conformation of the genome and its impact on gene expression. However, these studies frequently do not consider parent-of-origin differences, such as genomic imprinting, which result in monoallelic expression. In addition, genome-wide allele-specific chromatin conformation associations have not been extensively explored. There are...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ec8dca1e-c50f-5d01-8694-89beaf1cac48
DOI: 10.1101/2022.04.26.489502

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Widespread allele-specific topological domains in the human genome are not confined to imprinted gene clustersDOI 10.1101/2022.04.26.489502Read

Widespread allele-specific topological domains in the human genome are not confined to imprinted gene clusters.Semantic proximity Read

HUGIn: Hi-C Unifying Genomic InterrogatorSemantic proximity Read

Interrogation of allelic chromatin states in human cells by high-density ChIP-genotyping.Semantic proximity Read

Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.Semantic proximity Read

Atlas of imprinted and allele-specific DNA methylation in the human bodySemantic proximity Read

Extensive folding variability between homologous chromosomes in mammalian cells.Semantic proximity Read

Integration of phased Hi-C and molecular phenotype data to study genetic and epigenetic effects on chromatin loopingSemantic proximity Read

Integrative analysis of haplotype-resolved epigenomes across human tissues.Semantic proximity Read

Chromosome-wide analysis of parental allele-specific chromatin and DNA methylation.Semantic proximity Read

HUGIn: Hi-C Unifying Genomic Interrogator.Semantic proximity Read

Parental allele-specific genome architecture and transcription during the cell cycleSemantic proximity Read

Differential 3D genome architecture and imprinted gene expression: cause or consequence?Semantic proximity Read