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Article

Integrative analysis of haplotype-resolved epigenomes across human tissues.

Nature - 19 Feb 2015

Leung Danny, Jung Inkyung, Rajagopal Nisha, Schmitt Anthony, Selvaraj Siddarth, Lee Ah Young, Yen Chia-An, Lin Shin, Lin Yiing, Qiu Yunjiang, Xie Wei, Yue Feng, Hariharan Manoj, Ray Pradipta, Kuan Samantha, Edsall Lee, Yang Hongbo, Chi Neil C, Zhang Michael Q, Ecker Joseph R, Ren Bing

Abstract excerpt

Allelic differences between the two homologous chromosomes can affect the propensity of inheritance in humans; however, the extent of such differences in the human genome has yet to be fully explored. Here we delineate allelic chromatin modifications and transcriptomes among a broad set of human tissues, enabled by a chromosome-spanning haplotype reconstruction strategy. The resulting large collection of...

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Identifiers

PMID: 25693566
DOI: 10.1038/nature14217
PMCID: PMC4449149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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