Article

Evolutionary tracking of cancer haplotypes at single-cell resolution

2021-06-06

Abstract excerpt

Cancer genomes exhibit extensive chromosomal copy number changes and structural variation, yet how allele specific alterations drive cancer genome evolution remains unclear. Here, through application of a new computational approach we report allele specific copy number alterations in 11,097 single cell whole genomes from genetically engineered mammary epithelial cells and 21,852 cells from high grade serous ovaria...

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Literature Corpus work: 4a3acb73-41da-5015-9329-f6ad1737da37
DOI: 10.1101/2021.06.04.447031

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