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Article

Interrogation of allelic chromatin states in human cells by high-density ChIP-genotyping.

Epigenetics - 1 Sept 2014

Light Nicholas, Adoue Véronique, Ge Bing, Chen Shu-Huang, Kwan Tony, Pastinen Tomi

Abstract excerpt

Allele-specific (AS) assessment of chromatin has the potential to elucidate specific cis-regulatory mechanisms, which are predicted to underlie the majority of the known genetic associations to complex disease. However, development of chromatin landscapes at allelic resolution has been challenging since sites of variable signal strength require substantial read depths not commonly applied in sequencing based...

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Identifiers

PMID: 25055051
DOI: 10.4161/epi.29920
PMCID: PMC4169016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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