Article

Unsupervised reference-free inference reveals unrecognized regulated transcriptomic complexity in human single cells

2022-12-07

Abstract excerpt

Myriad mechanisms diversify the sequence content of eukaryotic transcripts at both the DNA and RNA levels, leading to profound functional consequences. Examples of this diversity include RNA splicing and V(D)J recombination. Currently, these mechanisms are detected using fragmented bioinformatic tools that require predefining a form of transcript diversification and rely on alignment to an incomplete reference gen...

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Literature Corpus work: 23572aee-74b2-54a1-a746-97dd81954f1a
DOI: 10.1101/2022.12.06.519414

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