Article

SIngle cell level Genotyping Using scRna Data (SIGURD)

2024-07-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Motivation</h4> By accounting for variants within measured transcripts, it is possible to evaluate the status of somatic variants using single-cell RNA-sequencing (scRNA-seq) and to characterize their clonality. However, the sparsity (very few reads per transcript) or bias in protocols (favoring 3’ ends of the transcripts) makes the chance of capturing somatic variants very unlikely. This c...

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Literature Corpus work: f7730a9e-7cc2-56ad-a82f-af0a985e6358
DOI: 10.1101/2024.07.16.603737

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