Article

The ENCODE4 long-read RNA-seq collection reveals distinct classes of transcript structure diversity

2023-05-16

Abstract excerpt

The majority of mammalian genes encode multiple transcript isoforms that result from differential promoter use, changes in exonic splicing, and alternative 3’ end choice. Detecting and quantifying transcript isoforms across tissues, cell types, and species has been extremely challenging because transcripts are much longer than the short reads normally used for RNA-seq. By contrast, long-read RNA-seq (LR-RNA-seq) g...

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Literature Corpus work: ab10afb3-fd92-5498-90d3-a06f8f0718c2
DOI: 10.1101/2023.05.15.540865

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