Article

SCOTCH: isoform-level characterization of gene expression through long-read single-cell RNA sequencing

2024-04-30

Abstract excerpt

Recent advances in long-read single-cell transcriptome sequencing (lr-scRNA-Seq) enable full-length isoform profiling at single-cell resolution. We present SCOTCH (Single-Cell Omics for Transcriptome CHaracterization), an end-to-end, platform-independent pipeline for isoform characterization from lr-scRNA-Seq data, supporting Nanopore and PacBio sequencing as well as 10X Genomics and Parse Biosciences protocols. S...

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Literature Corpus work: c8b8a96a-16bb-5c6e-a349-fabb09085088
DOI: 10.1101/2024.04.29.590597

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