Article

Robust clustering and interpretation of scRNA-seq data using reference component analysis

2021-02-17

Abstract excerpt

<h4>Motivation</h4> The transcriptomic diversity of the hundreds of cell types in the human body can be analysed in unprecedented detail using single cell (SC) technologies. Though clustering of cellular transcriptomes is the default technique for defining cell types and subtypes, single cell clustering can be strongly influenced by technical variation. In fact, the prevalent unsupervised clustering algorithms ca...

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Literature Corpus work: 408f3bef-d61e-5326-ae40-b3ef274bd505
DOI: 10.1101/2021.02.16.431527

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