Article

Controlled Noise: Evidence of Epigenetic Regulation of Single-Cell Expression Variability

2024-04-14

Abstract excerpt

<h4>Motivation</h4> Understanding single-cell expression variability (scEV) or gene expression noise among cells of the same type and state is crucial for delineating population-level cellular function. While epigenetic mechanisms are widely implicated in gene expression regulation, a definitive link between chromatin accessibility and scEV remains elusive. Advances in single-cell techniques now enable simultaneo...

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Literature Corpus work: 347fb1f0-1de5-5fe8-bbe6-4d3c0b27848b
DOI: 10.1101/2024.04.10.588957

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