Article

Integrated mapping of human meniscus and cartilage eQTLs reveals shared and distinct osteoarthritis genetic drivers

2026-04-16

Abstract excerpt

Osteoarthritis (OA) is a prevalent musculoskeletal disorder and a leading cause of global disability. Although meniscal damage is a major risk factor of OA pathogenesis, genetic regulatory studies have remained largely confined to articular cartilage. Here, we establish the first comprehensive expression quantitative trait locus (eQTL) map integrating whole-genome sequencing and bulk transcriptomics from human men...

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Literature Corpus work: 2319738a-f8fa-572c-83d2-1234d7ac1989
DOI: 10.64898/2026.04.12.26350702

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