Article

Transcriptome analysis in osteoarthritis primary tissues identifies high-confidence effector genes

2024-12-05

Abstract excerpt

Osteoarthritis, a whole-joint degenerative disorder, is a major public health burden that affects nearly 600 million individuals worldwide, but no disease-modifying treatment exists. Molecular profiling of relevant tissues is crucial for understanding the biological mechanisms underlying disease development. Here, we generate a comprehensive map of transcriptional regulation in disease-relevant primary tissues fro...

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Literature Corpus work: d85b5a87-7839-5f2b-aa49-34ce77df16ff
DOI: 10.1101/2024.12.04.24318411

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