Article
Genetic transcriptional regulation profiling of cartilage reveals pathogenesis of osteoarthritis
26 Jun 2025
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified more than one hundred risk loci for osteoarthritis (OA). Identifying the effector genes and deciphering the underlying regulatory mechanisms are of great importance but remains challenging due to limited availability of OA-related tissue data. This study aims to address this issue by generating a cartilage expression quantitative trait loci...
Topics
Join the communities discussing this publication.