Article
Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank
2018-10-25
Abstract excerpt
Osteoarthritis is the most common musculoskeletal disease and the leading cause of disability globally. Here, we perform the largest genome-wide association study for osteoarthritis to date (77,052 cases and 378,169 controls), analysing 4 phenotypes: knee osteoarthritis, hip osteoarthritis, knee and/or hip osteoarthritis, and any osteoarthritis. We discover 64 signals, 52 of them novel, more than doubling the numb...
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Identifiers and source
- Literature Corpus work
- bcd25d3e-dd0d-53c4-a2d7-000a6a8affdf
- DOI
- 10.1101/453530