Article

Minimal phenotyping yields GWAS hits of reduced specificity for major depression

2018-10-11

Abstract excerpt

Minimal phenotyping refers to the reliance on the use of a small number of self-report items for disease case identification. This strategy has been applied to genome-wide association studies (GWAS) of major depressive disorder (MDD). Here we report that the genotype derived heritability (h 2 SNP ) of depression defined by minimal phenotyping (14%, SE = 0.8%) is lower than strictly defined MDD (26%, SE = 2.2%). T...

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Literature Corpus work: 22f120fd-184f-5ba9-9ce4-5cd29c25d070
DOI: 10.1101/440735

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