Article

Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

2019-02-13

Abstract excerpt

Major depressive disorder and neuroticism share a large genetic basis. We sought to determine whether this shared basis could be decomposed to identify genetic factors that are specific to depression. We analysed two sets of summary statistics from genome-wide association studies of depression (from the Psychiatric Genomics Consortium and 23andMe) and compared them to GWAS of neuroticism (from UK Biobank). First,...

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Literature Corpus work: bcd08cfc-3edf-5e32-afec-da308e2f4675
DOI: 10.1101/547828

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