Article
The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes.
Biological psychiatry - 1 Aug 2022
Mitchell Brittany L, Campos Adrian I, Whiteman David C, Olsen Catherine M, Gordon Scott D, Walker Adam J, Dean Olivia M, Berk Michael, Hickie Ian B, Medland Sarah E, Wray Naomi R, Martin Nicholas G, Byrne Enda M
Abstract excerpt
BACKGROUND: Major depressive disorder (MDD) is a common and highly heterogeneous psychiatric disorder, but little is known about the genetic characterization of this heterogeneity. Understanding the genetic etiology of MDD can be challenging because large sample sizes are needed for gene discovery-often achieved with a trade-off in the depth of phenotyping. METHODS: The Australian Genetics of Depression Study is...
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