Article

Symptom-specific genetics reveal heterogeneity within major depressive disorder

2026-03-25

Abstract excerpt

<h4>Background</h4> Major Depressive Disorder (MDD) is clinically and biologically heterogeneous. Here, we leveraged the genetics of individual depressive symptoms to dissect the disorder’s underlying heterogeneity. <h4>Methods</h4> We utilized the BIObanks Netherlands Internet Collaboration (BIONIC). A series of genome-wide association studies (effective- N range: 14,407 - 47,110) compared controls (N=48,286)...

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Literature Corpus work: a4ddbb16-f2a0-58eb-92c1-c0117cda9b0c
DOI: 10.64898/2026.03.24.26349158

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