Article

Using Major Depression Polygenic Risk Scores to Explore the Depressive Symptom Continuum

2020-02-26

Abstract excerpt

<h4>Background</h4> It is not clear whether major depression (MD) is a categorical disorder or if depressive symptoms exist on a continuum based on severity. Observational studies comparing sub-threshold and clinical depression suggest MD is continuous, but many do not explore the full continuum and are yet to consider genetics as a risk factor. This study sought to understand if polygenic risk for MD could provi...

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Literature Corpus work: afe6b5d8-bd51-56f0-a3f7-3ea40194ae92
DOI: 10.1101/2020.02.25.962704

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