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Article

Polygenic Analyses Show Important Differences Between Major Depressive Disorder Symptoms Measured Using Various Instruments.

Biological psychiatry - 15 Jun 2024

Huang Lianyun, Tang Sonja, Rietkerk Jolien, Appadurai Vivek, Krebs Morten Dybdahl, Schork Andrew J, Werge Thomas, Zuber Verena, Kendler Kenneth, Cai Na

Abstract excerpt

BACKGROUND: Symptoms of major depressive disorder (MDD) are commonly assessed using self-rating instruments like the Patient Health Questionnaire-9 (PHQ-9) (current symptoms) and the Composite International Diagnostic Interview Short-Form (CIDI-SF) (worst-episode symptoms). We performed a systematic comparison between them for their genetic architecture and utility in investigating MDD heterogeneity. METHODS:...

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Source

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Identifiers

PMID: 38056704
DOI: 10.1016/j.biopsych.2023.11.021
PMCID: PMC11139567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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