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Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of <i>Plasmodium falciparum</i> reveals several inhibitory compounds

2019-09-13

Abstract excerpt

To identify potential inhibitors of egress and invasion in the asexual blood stage of Plasmodium falciparum , we screened the Medicines for Malaria Venture (MMV) Pathogen Box. This compound library comprises of 400 drugs against neglected tropical diseases, including 125 with antimalarial activity. For this screen, we utilised transgenic parasites expressing a bioluminescent reporter, Nanoluciferase (Nluc), to me...

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Literature Corpus work
217c459c-0552-5ead-80f4-e95bb757da05
DOI
10.1101/768648
Open publication

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Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of <i>Plasmodium falciparum</i> reveals several inhibitory compoundsDOI 10.1101/768648
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