Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules

16 Jan 2018

Abstract excerpt

The phylum Apicomplexa includes many human and animal pathogens, such as Plasmodium falciparum (human malaria) and Toxoplasma gondii (human and animal toxoplasmosis). Widespread resistance to current antimalarials and the lack of a commercial vaccine necessitate novel pharmacological interventions with distinct modes of action against malaria. For toxoplasmosis, new drugs to effectively eliminate tissue-dwelling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to Mosquito-borne diseases and control
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29359192
DOI: 10.1128/msphere.00534-17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box MoleculesPMID 29359192Read ↗

Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of <i>Plasmodium falciparum</i> reveals several inhibitory compoundsSemantic proximity Read ↗

Antimalarial Drug Discovery from Natural and Synthetic SourcesSemantic proximity Read ↗

Targeting the apicoplast in malariaSemantic proximity Read ↗

Multistage inhibitors of the malaria parasite: Emerging hope for chemoprotection and malaria eradicationSemantic proximity Read ↗

Multistage and transmission-blocking tubulin targeting potent antimalarial discovered from the open access MMV Pathogen BoxSemantic proximity Read ↗

Promising antimalarial hits from phenotypic screens: a review of recently-described multi-stage actives and their modes of actionSemantic proximity Read ↗

Repurposing of the Open Access Malaria Box for Kinetoplastid Diseases Identifies Novel Active Scaffolds against TrypanosomatidsSemantic proximity Read ↗

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infectionsSemantic proximity Read ↗

The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected DiseasesSemantic proximity Read ↗

Novel antimalarial drug targets: hope for new antimalarial drugsSemantic proximity Read ↗

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response BoxSemantic proximity Read ↗

Antiparasitic chemotherapy: from genomes to mechanisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.